Citation Information :
Durga N, Shabina M, Philomina BJ. Acute disseminated candidiasis caused by Candida tropicalis in a child with acute lymphoblastic leukaemia. 2023; 25 (2):64-67.
Candidaemia due to Candida spp. is a major cause of morbidity and mortality in the healthcare settings. Candida tropicalis is a globally emerging opportunistic pathogen causing invasive infection in immunocompromised patients. It is the most common non-albicans candida causing infections in humans. Clinical manifestations may vary from simple oral thrush to widely disseminated systemic infections, especially in immunocompromised patients. We report a case of an eight-year-old child with B-cell acute lymphoblastic leukaemia who developed widely disseminated candidiasis caused by Candida tropicalis with oral, dermatologic, hepatic and renal manifestations post-chemotherapy. The patient was empirically started on tablet Fluconazole and Amphotericin B was added after antifungal susceptibility testing. Good clinical response was seen after she was treated with injection Caspofungin.
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