BACKGROUND: Hands are the main pathway of germ transmission during health care delivery. Health care associated infections are important cause for morbidity and mortality, reduced quality of life, prolonged hospital stay and are associated with increase in the health care cost each year1,2. Hand hygiene is a simple and low-cost measure to reduce health care associated infection. Hand hygiene has been recommended as an important strategy to help prevent the spread of COVID-19 infection in hospitals3. This study aims at assessing the hand hygiene compliance among health care workers during Covid 19 pandemic in ICU settings. AIMS AND OBJECTIVES: To assess the compliance of hand hygiene among health care workers during COVID -19 pandemic in ICU's settings. To increase the compliance of hand hygiene among health care workers during COVID-19 pandemic. SETTINGS AND DESIGN: A prospective study was conducted in a 250 bedded tertiary care multispeciality hospital from March 20 to November 20. We followed direct observation method for assessing WHO's five moments of hand hygiene during this covid -19 pandemic in ICU's which included MICU-1, MICU-2, SICU, NICU, NSICU, CCU, CTICU. Study was carried on health care workers like doctors, nurses and others which included housekeeping, food and beverage, dietary, pharmacy staff and physiotherapy staff. METHODS AND MATERIAL: Hand hygiene is assessed by direct observation method.5 moments of hand hygiene has been observed like before aseptic task, before patient contact, after patient contact, after touching patient surroundings and after exposure to contaminated fluids. STATISTICAL ANALYSIS USED: Microsoft excel RESULTS: We used direct observation method for assessing 5 moments of hand hygiene which is a gold standard method. Percentage of compliance for hand hygiene for nurses, doctors and others were 72.4, 71.4 and 68.1 and overall compliance was 70.55 respectively during March 20. Later by November 20, percentage of compliance for nurses, doctors and others were 91.9, 88.5 and 84.5 and overall compliance was 88.2. So, there was a improvement in the compliance among nurses, doctors and others from 72.4, 71.4, 68.1 to 91.9, 88.5, 84.5 respectively. CONCLUSION: The overall percentage of compliance was 70.55 in the month of March 2020, which showed improvement by November 2020 to 88.2 during the Covid-19 pandemic in seven ICU's.