Serological prevalence of scrub typhus among febrile patients from a tertiary care hospital in South Kerala
Swetha Sivaraman, Ivy Viswamohanan, Ganga Raju Krishna, Ashish Jithendranath, Ramani Bai
Keywords :
Scub typhus, ELISA, rickettsia
Citation Information :
Sivaraman S, Viswamohanan I, Krishna GR, Jithendranath A, Bai R. Serological prevalence of scrub typhus among febrile patients from a tertiary care hospital in South Kerala. 2020; 22 (1):41-43.
Scrub typhus, a potentially fatal rickettsial infection, is common in India. As the clinical features include fever, vomiting, headache, respiratory infection and rashes the differential diagnosis includes Enteric fever, Dengue, Leptospirosis and Malaria. Though many methods are available for diagnosis, IgM ELISA is the most sensitive method. A prospective study was carried out at the Sree Gokulam Medical College Thiruvananthapuram from January 2019 to December 31 2019. A total of 178 samples were screened for scrub typhus. Commercially available IgM ELISA was used. Out of 178 samples 28 samples were positive for scrub typhus(15.7%). 20-40 years age groups showed maximum number of cases and cases were more from June to September. Males were more commonly affected (57%). Scrub typhus is considered one of the important differential diagnoses of pyrexia of unknown origin in this area.
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