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VOLUME 21 , ISSUE 2 ( July-December, 2019 ) > List of Articles

Original Article

Seroprevalence of hepatitis E in healthy adults attending a tertiary care centre in Central Kerala

KG Chithira, Reena John, Prithi Nair

Keywords : Antenatal women, anti-hepatitis E virus immunoglobulin G, blood donors, Central Kerala, hepatitis E virus

Citation Information : Chithira K, John R, Nair P. Seroprevalence of hepatitis E in healthy adults attending a tertiary care centre in Central Kerala. 2019; 21 (2):80-84.

DOI: 10.4103/jacm.jacm_33_19

License: CC BY-NC 4.0

Published Online: 17-01-2020

Copyright Statement:  Copyright © 2019; Wolters Kluwer India Pvt. Ltd.


Abstract

BACKGROUND: Hepatitis E virus (HEV) is emerging globally as a leading cause of an acute and generally self-limited hepatitis but is associated with a higher mortality, especially during pregnancy. AIM: The purpose of this study was to estimate the seroprevalence of hepatitis E infection among adults with no previous history of jaundice/liver disease, in a tertiary care centre at Thrissur. STUDY SETTING AND DESIGN: Hospital based cross sectional study was carried out in Government Medical College, Thrissur. MATERIALS AND METHODS: Anti-HEV IgG was detected by using commercially available enzyme linked immunosorbent assay. RESULT: The seroprevalence of HEV among blood donors and antenatal was approximately 1.2%. CONCLUSION: HEV is less prevalent in this region. The low seropositivity among healthy adults shows an increased susceptibility to HEV infection. Since there is an increase in migrantsfrom high endemic area, screening for HEV in adult population especially pregnant females is desirable.

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