Antimicrobial resistance is on an increasing trend worldwide. The WHO has declared it to be a ‘Global Threat’ in the year 2015. Due to this growing concern, antimicrobial stewardship (AMS) programmes have been implemented all over the world in the last few decades. The main challenge in AMS programme is the long-term sustenance, and hence, there is no worldwide agreed consensus on the ‘best’ AMS strategies. This review article provides an overview of the evolution of AMS strategies through the years and highlights the clinical effectiveness and cost-effectiveness of the strategies implemented till date.
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