Citation Information :
Sharma P, Sharma S. Non-dermatophytes emerging as predominant cause of onychomycosis in a tertiary care centre in rural part of Punjab, India. 2016; 18 (1):36-39.
Background: Onychomycosis is most commonly caused by dermatophytes belonging to the genus Trichophyton. However, Candida spp. and non-dermatophyte moulds may also be responsible. Up to 10% of cases of onychomycosis are caused by non-dermatophyte moulds and these are becoming more common worldwide.
Materials and Methods: A retrospective analysis for a period of one year was undertaken to know the prevalence of different fung causing onychomycosis in a tertiary care hospital. Nail samples of fingers and toes collected from patients presenting with clinically suspected onychomycosis were processed by standard methods.
Results: Of the 87 clinically suspected cases of onychomycosis, non-dermatophyte moulds were the most common pathogens isolated in 24 (53.33%) patients, followed by dermatophytes in 12 (26.66%) patients and Candida spp. in 9 (20%). Among the non-dermatophyte moulds, Aspergillus flavus was the most common isolate found in 15 (62.5%) cases.
Conclusion: The predominant isolate obtained in this study was non-dermatophyte moulds. Among moulds, Aspergillus spp. was the most common isolate.
Thomas J, Jacobson GA, Narkowicz CK, Peterson GM, Burnet H, Sharpe C. Toenail onychomycosis: An important global disease burden. J Clin Pharm Ther 2010;35:497-519.
Gupta AK, Gupta MA, Summerbell RC, Cooper EA, Konnikov N, Albresk D, et al. The epidemiology of onychomycosis: Possible role of smoking and peripheral arterial disease. J Eur Acad Dermatol Venereol 2000;14:466-9.
Mayser P, Freund V, Budihardja D. Toenail onychomycosis in diabetic patients: Issues and management. Am J Clin Dermatol 2009;10:211-20.
Surjushe A, Kamath R, Obera C, Saple D, Thakre M, Dharmshale S, et al. A clinical and mycological study of onychomycosis in HIV infection. Indian J Dermatol Venereol Leprol 2007;73:397-401.
Hay RJ, Baran R. Onychomycosis: A proposed revision of the clinical classification. J Am Acad Dermatol 2011;65:1219-27.
Elewsk BE, Charif MA. Prevalence of onychomycosis in patients attending a dermatology clinic in northeastern Ohio for other conditions. Arch Dermatol 1997;133:1172-3.
Koneman EW. Color Atlas and Text Book of Diagnostic Microbiology. 6th ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2006.
Godoy-Martinez P, Nunes FG, Tomimori-Yamashita J, Urrutia M, Zaror L, Silva V, et al. Onychomycosis in São Paulo, Brazil. Mycopathologia 2009;168:111-6.
Sehgal VN, Srivastava G, Dogra S, Chaudhary A, Adhikar T. Onychomycosis: An Asian perspective. Skinmed 2010;8:37-45.
Raghavendra KR, Yadav D, Kumar A, Sharma M, Bhuria J, Chand AE. The nondermatophyte molds: Emerging as leading cause of onychomycosis in South-East Rajasthan. Indian Dermatol Online J 2015;6:92-7.
Sanjiv A, Shalin M, Charoo H. Etiological agents of onychomycosis from a tertiary care hospital in central Delhi, India. Indian J Fundam Appl Life Sc 2011;1:11-4.
Farwa U, Abbas SA, Mirza IA, Amjad A, Ikram A, Malik N, et al. Non-dermatophyte moulds as pathogens of onychomycosis. J Coll Physicians Surg Pak 2011;21:597-600.
Yenisehirl G, Bulut Y, Sezer E, Günday E. Onychomycosis infections in the middle Black Sea region, Turkey. Int J Dermatol 2009;48:956-9.
Elewsk BE. Diagnostic techniques for confirming onychomycosis. J Am Acad Dermatol 1996;35(3 Pt 2):S6-9.
EL Bataw MM, Arnaot H, Shoeib S, Bosseila M, EL Fangary M, Helmy AS. Prevalence of non-dermatophyte molds in patients with abnormal nails. Egypt Dermatol Online J 2006;2:12.
Gupta M, Sharma NL, Kanga AK, Mahajan VK, Tegta GR. Onychomycosis: Clinico-mycologic study of 130 patients from Himachal Pradesh, India. Indian J Dermatol Venereol Leprol 2007;73:389-92.
Veer P, Patwardhan NS, Damle AS. Study of onychomycosis: Prevailing fung and pattern of infection. Indian J Med Microbiol 2007;25:53-6.
Ahmad M, Gupta S, Gupte S. A clinico-mycological study of onychomycosis. Egypt Dermatol Online J 2010;6:1-9.
Das NK, Ghosh P, Das S, Bhattacharya S, Dutta RN, Sengupta SR. A study on the etiological agent and clinico-mycological correlation of fingernail onychomycosis in eastern India. Indian J Dermatol 2008;53:75-9.
Jesudanam TM, Rao GR, Lakshm DJ, Kumar GR. Onychomycosis: A significant medical problem. Indian J Dermatol Venereol Leprol 2002;68:326-9.
Singal A, Khanna D. Onychomycosis: Diagnosis and management. Indian J Dermatol Venereol Leprol 2011;77:659-72.