Determination of Vancomycin, Teicoplanin and Linezolid resistance among Staphylococcal isolates from a tertiary care hospital
Shashikala Shivaprakasha
Keywords :
CoNS glycopeptides resistance, CoNS Linezolid, Teicoplanin resistance, CoNS Vancomycin, S. epidermidis, S. aureus, S. haemolyticus
Citation Information :
Shivaprakasha S. Determination of Vancomycin, Teicoplanin and Linezolid resistance among Staphylococcal isolates from a tertiary care hospital. 2015; 17 (1):3-6.
Background and Objectives: Increasing reports of Vancomycin creep have been observed in both Methicillin sensitive and Methicillin resistant staphylococcal isolates. The objective of this study was to determine the sensitivity pattern among clinical isolates of Methicillin sensitive and Methicillin resistant Staphylococcus aureus (MRSA), S. epidermidis, S. haemolyticus, to Vancomycin, Teicoplanin and Linezolid.
Materials and Methods: A total of 82 S. aureus, 34 S. epidermidis and 26 S. haemolyticus isolated during Jan 2011 to Dec 2011 were included in the study. None of the S. aureus isolates were resistant to Vancomycin and Linezolid. Only one MRSA isolate was resistant to Teicoplanin. Vancomycin resistant strains among Methicillin resistant S. epidermidis was one (4.3%) and among S. haemolyticus was two (8.3%) respectively. Teicoplanin resistant strains among Methicillin resistant S. epidermidis was six (26.1%) and among S. haemolyticus was two (8.3%). Linezolid resistant strains among Methicillin resistant S. epidermidis was two (8.7%) and among S. haemolyticus was one (4.2%).
Conclusion: Emergence of Vancomycin, Teicoplanin and Linezolid resistance among Methicillin resistant coagulase negative staphylococci (CoNS) is alarming limiting the therapeutic options.
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