Mucormycosis caused by Apophysomyces elegans is an emerging disease not only in immunocompromised hosts but also in the immunocompetent. Here, we report a case of invasive necrotizing fasciitis of left thigh due to Apophysomyces elegans in a diabetic. Below knee amputation of gangrenous right leg was done 20 days before this developed. Broad aseptate hyphae were observed in necrosed tissues. Surgical debridement was done and Amphotericin B was recommended. Isolate recovered in culture was identified as A. elegans based on induction of sporulation on water agar and other modified methods. Patient expired due to sepsis.
Gomes MZ, Lewis RE, Kontoyiannis DP. Mucormycosis caused by unusual Mucormycetes, non-Rhizopus, -Mucor, and -Lichtheimia species. Clin Microbiol Rev 2011; 24:411-45.
Chakrabarti A, Ghosh A, Prasad GS, David JK, Gupta S, Das A, et al. Apophysomyses elegans: An emerging zygomycete in India. J Clin Microbiol 2003;41:783-8.
Chander J, Kaur J, Attri A, Mohan H. Primary cutaneous zygomycosis from a tertiary care centre in north-west India. Indian J Med Res 2010;131:765-70.
Jain D, Kumar Y, Vasishta RK, Rajesh L, Pattari SK, Chakrabarti A. Zygomycotic necrotizing fasciitis in immunocompetent patients: A series of 18 cases. Mod Pathol 2006;19:1221-6.
Ellis JJ, Ajello L. An unusual source for Apophysomyces elegans and a method for stimulating sporulation of Saksenaea vasiformis. Mycologia 1982;74:144-5.
Padhye AA, Ajello L. Simple method of inducing sporulation by Apophysomyces elegans and Saksenaea vasiformis. J Clin Microbiol 1988;26:1861-3.
Misra PC, Srivastava KJ, Lata K. Apophysomyces, a new genus of Mucorales. Mycotaxon 1979;8:377-82.
