Journal of The Academy of Clinical Microbiologists

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VOLUME 15 , ISSUE 2 ( July-December, 2013 ) > List of Articles

CASE REPORT (VIROLOGY)

Post-natally acquired cytomegalovirus infection in a pre-term infant

Shabina Balakrishnan, Rema Devi, Babu Francis, Anitha Moorkoth

Keywords : Blood transfusion, cytomegalovirus infection, Ganciclovir, low birth weight pre-mature infant, post-natal

Citation Information : Balakrishnan S, Devi R, Francis B, Moorkoth A. Post-natally acquired cytomegalovirus infection in a pre-term infant. 2013; 15 (2):72-74.

DOI: 10.4103/0972-1282.124593

License: CC BY-NC-SA 4.0

Published Online: 20-07-2024

Copyright Statement:  Copyright © 2013; Wolters Kluwer India Pvt. Ltd.


Abstract

Cytomegalovirus (CMV) infection is the most common intra-uterine and peri-natal viral infection. CMV infections in neonates are acquired by aspiration of cervico-vaginal secretions during birth, through breast milk and from exposure to blood products. Most of the infections in neonates are asymptomatic. Pre-term infants tend to show higher susceptibility to peri-natal and post-natal infections. We report CMV infection in a pre-term low birth weight infant who presented with fever, and respiratory distress due to pneumonitis and was successfully treated with Ganciclovir.


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  1. Cytomegalovirus infection. Paediatr Rev 2012;33:156-63.
  2. Congenital cytomegalovirus infection in a highly seropositive semi-urban population in India. Pediatr Infect Dis J 2008;27:841-3.
  3. Paediatric Cytomegalovirus infection (available form http://www.emedicine.medscape.com/article/963090-overview#a0199).
  4. Breast milk and the risk of cytomegalovirus infection. N Engl J Med 1980;302:1073-6.
  5. Cytomegalovirus infections in neonates acquired by blood transfusions. Pediatr Infect Dis 1983;2:114-8.
  6. Severe postnatal cytomegalovirus infection with multisystem involvement in an extremely low birth weight infant. J Perinatol 2012;32:72-4.
  7. Cytomegalovirus infection in the fetus and neonate. Neo Rev 2005;6:e38-45.
  8. Transfusion-acquired cytomegalovirus infection in newborn infants. Am J Dis Child 1974;128:478-83.
  9. Sequelae of acquired cytomegalovirus infection in premature and sick term infants. J Pediatr 1985;107:451-6.
  10. Use of ganciclovir in the treatment of acquired cytomegalovirus disease in a preterm infant. Can J Infect Dis 1990;1:28-30.
  11. Congenital and perinatal cytomegalovirus infection (available form: http://www.merckmanuals.com/professional/pediatrics/...infection_cmv.html). Merck Man Health Care Prof; 2009.
  12. From Harrison's Principles of Internal Medicine. Vol. 1, 16 th ed. 2005. p. 1049-52.
  13. Transfusion-related cytomegalovirus infection among very low birth weight infants in an endemic area. J Korean Med Sci 2006;21:5-10.
  14. Cytomegalovirus infection in neonates following exchange transfusion. Indian J Pediatr 2006;73:519-21.
  15. Severe postnatally acquired cytomegalovirus infection presenting with colitis, pneumonitis and sepsis-like syndrome in an extremely low birthweight infant. Neonatology 2010;97:339-45.
  16. Ganciclovir therapy for congenital cytomegalovirus infection in six infants. Pediatr Infect Dis J 2005;24:782-5.
  17. Congenital and perinatal cytomegalovirus infection. Korean J Pediatr 2010;53:14-20.
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