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ORIGINAL ARTICLE
Year : 2016  |  Volume : 18  |  Issue : 1  |  Page : 32-35

Characterisation and antifungal susceptibility profile of Candida species isolated froma tertiary care hospital


Department of Microbiology, Government Medical College, Thiruvananthapuram, Kerala, India

Correspondence Address:
Prasadini Guru
Department of Microbiology, Government Medical College, Thiruvananthapuram, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-1282.184753

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Background: An increase in the prevalence of infections caused by non-albicans Candida (NAC) has been reported from many parts of the world. The increased isolation rates of NAC and a gradual shift in the antifungal susceptibility profile underlines the need for early and accurate diagnosis of Candida infections along with antifungal susceptibility testing. Aim: The aim of this study is to characterise Candida spp. isolated from various clinical samples and determine the antifungal susceptibility pattern. Settings and Design: This study was conducted in the Department of Microbiology, at a tertiary care referral centre, over a period of one year and included 200 Candida spp. Materials and Methods: Candida isolates were characterised by conventional techniques and CHROMagar. Antifungal susceptibility test was performed using disc diffusion method. Clinical details and risk factors were recorded and analysed. Results and Conclusions: Candida albicans was the most common species isolated, followed by Candida tropicalis. The Candida isolates were more susceptible to Amphotericin B than other antifungal agents tested. Diabetes mellitus appeared to be the most common predisposing factor for the Candida infections, followed by indiscriminate drug usage.


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